Angelo SASSAROLI¹, Fabrizio MARTELLI², Yukari TANIKAWA¹, Kenji TANAKA¹, Ryuichiro ARAKI³, Yoichi ONODERA¹ and Yukio YAMADA¹

¹Mechanical Engineering Laboratory, Material Science and Bioengineering Department, AIST, MITI, 1-2, Namiki, Tsukuba, Ibaraki, 305-8564 Japan, ²Dipartimento di Fisica dell'Universita' degli Studi di Firenze, Via Santa Marta 3, 50139 Firenze, Italy, ³Saitama Medical School, 38, Moro-Hongo, Moroyama, Saitama, 358-8564 Japan

(Received June 5, 2000; Accepted June 30, 2000)

The in vivo optical properties of a piglet brain were measured using a time-resolved system at three different wavelengths (759, 794, 824 nm). To separate the contribution of different head layers to the detected signals, the measurements were acquired from the surfaces of skin, skull, dura mater and brain. The source-detector distance was chosen to assure a mean penetration depth within each layer. Measurements were analyzed and compared with the results of other in vivo measurements reported in literature.

Key words : tissue optics, near infrared light imaging, near infrared light spectroscopy, optical properties, in vivo, in vitro, diffusion equation, Monte Carlo

kiso05@mmail.mel.go.jp