[OPTICAL REVIEW Vol. 20, No. 1 (2013) 19-25]
© 2013 The Japan Society of Applied Physics

Visualized Numerical Assessment for Near Infrared Diffuse Optical Tomography with Contrast-and-Size Detail Analysis

Liang-Yu CHEN1, Min-Cheng PAN2*, and Min-Chun PAN1,3

1Department of Mechanical Engineering, National Central University, Jhongli, Taoyuan 32001, Taiwan, R.O.C.
2Department of Electronic Engineering, Tungnan University, New Taipei City 222, Taiwan, R.O.C.
3Graduate Institute of Biomedical Engineering, National Central University, Jhongli, Taoyuan 32001, Taiwan, R.O.C.

(Received August 20, 2012; Revised October 25, 2012; Accepted November 22, 2012)

The purpose of this study is to propose an objective contrast-and-size detail (CSD) analysis for near infrared diffuse optical tomography (NIR DOT), of which the concept is derived from the subjective contrast detail (CD) analysis. We define a measure for numerical CSD analysis based on the resolution estimation of contrast and size. Following that, the contrast-and-size map of resolution can be calculated and displayed for each corresponding image in the map; furthermore, a CSD resolution curve can be plotted by calculating the average value of the projection corresponding to the physical quantity/axis (size or contrast). To provide some worked examples about the proposed CSD analysis evaluating the imaging performance of different reconstruction methods, Tikhonov regularization and edge-preserving regularization with different weighting functions were employed. Results suggested that using edge-preserving regularization with the generalized Lorentzian weighting function is the most attractive for the estimation of absorption-coefficient images.

Key words: contrast-and-size detail analysis, diffuse optical tomography, contrast detail analysis, optical-property image

*E-mail address: m2pan@mail.tnu.edu.tw